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Stimulants

Amphetamines

Amphetamines are a chemical class of stimulants, entactogens, hallucinogens, and other drugs. They feature a phenethylamine core with a methyl group attached to the alpha carbon resulting in amphetamine, along with additional substitutions.

    2-FA, 2-Fluoroamphetamine
    2-FMA, 2-Fluoromethamphetamine
    2-MA, 2-Methylamphetamine, Ortetamine
    3-FA, 3-Fluoroamphetamine
    3-FMA, 3-Fluoromethamphetamine
    β-Phenylmethamphetamine

Cathinones

Cathinones include some stimulants and entactogens, which are derivatives of cathinone. They feature a phenethylamine core with an alkyl group attached to the alpha carbon, and a ketone group attached to the beta carbon, along with additional substitutions.

    2-Fluoromethcathinone, 2-FMC[15]
    2-Methylethcathinone, 2-MEC[16]
    2-Methylmethcathinone, 2-MMC[17]
    3,4-Dimethylmethcathinone, 3,4-DMMC
    3-Chloromethcathinone, 3-CMC, Metaclephedrone, Clophedrone[18]
    3-Ethylethcathinone, 3-EEC[19]
    3-Fluoromethcathinone, 3-FMC
    3-Methoxymethcathinone, 3-MeOMC[20]
    3-Methylethcathinone, 3-MEC[21]
    3-Methylmethcathinone, 3-MMC
    4-Bromomethcathinone, 4-Bromomethcathinone, 4-BMC, Brephedrone
    4-Bromoethcathinone, 4-BEC
    4-Chloromethcathinone, 4-CMC, Clephedrone[22]
    4-Ethylethcathinone, 4-EEC
    4-Ethylmethcathinone, 4-EMC
    4-Fluoroethylmethcathinone, 4-EFMC
    4-Fluoromethcathinone, Flephedrone, 4-FMC
    4-Fluoro-NiPP, 4F-IVP, 4-Fluoro-N-Isopropylpentedrone, 4-Fluoro-α-Isopropylamino-Valerophenone, 4-Fluoro-iPAVP, 4-Fluoro-NPP[23]
    4-Fluoro-Piperidinopentiophenone, 4F-PPP
    4-Fluoropentedrone, 4-FPD [24]
    4-Methyl-α-Ethylaminopentiophenone, 4-MEAPP, N-Ethyl-4-Methylpentedrone[25]
    4-Methylbuphedrone, 4-MeMABP, BZ-6378
    4-Methylcathinone, 4-MC, Normephedrone
    4-Methyldimethcathinone, 4-MDMC [26]
    4-Methylethcathinone, 4-MEC
    Mexedrone, 3-methoxy-2-(methylamino)-1-(4-methylphenyl)propan-1-one
    4-Methylpentedrone, 4-MPD
    4-Methylpropylcathinone, 4-MPC
    4-Sulfonyldimethcathinone, 4-SMC, 4-SDMC
    Benzedrone, 4-MBC
    Buphedrone, α-Methylamino-Butyrophenone, MABP
    DL-4662, Dimethoxyethylpentedrone[27]
    Ethcathinone, EC
    Hexedrone, α-Methylamino-Caprophenone
    4-Methylmethcathinone, Mephedrone, 4-MMC, 4-Methylephedrone, "MCAT"
    4-Methoxymethcathinone, Methedrone, βk-PMMA, 4-Methoxyephedrone, 4-MeoMC
    Mexedrone, Mephedrone methyl ether[28]
    N,N-Diethyl-4-Methcathinone, N,N-DEMC
    N-Ethylbuphedrone, NEB
    4-Fluoro-N-Ethylbuphedrone, 4-Fluoro-NEB, 4-FNEB
    NPP, α-Isopropylamino-Valerophenone, iPAVP, N-Isopropylpentedrone, NiPP
    Pentedrone, α-Methylamino-Valerophenone, MAVP, PD
    α-Ethylaminopentiophenone, EAPP, N-Ethyl-Pentedrone[25]
    βk-IVP, Indanyl-N-Ethyl-Pentedrone

Pyrrolidines and Pyrrolidinophenones

Pyrrolidines are amphetamines with a pyrrolidine group. Pyrrolidinophenones (also called Pyrovalerones) are cathinones (βk-amphetamines) with a pyrrolidine group.

    Diphenylprolinol, D2PM
    2-Diphenylmethylpyrrolidine, Desoxy-D2PM
    DMOPP, 3,4-Dimethoxy-Pyrrolidinoamphetamine
    α-Pyrrolidinopropiophenone, α-PPP
    3',4'-Methylenedioxy-α-pyrrolidinopropiophenone, MDPPP, 3,4-MD-α-PPP
    4'-Methoxy-α-pyrrolidinopropiophenone, MOPPP, 4-MeO-α-PPP
    4'-Methyl-α-pyrrolidinopropiophenone, 4-MePPP, MPPP, MαPPP
    α-Pyrrolidinobutiophenone, α-PBP
    3',4'-Methylenedioxy-α-pyrrolidinobutiophenone, MDPBP, 3,4-MD-α-PBP
    4'-Fluoro-α-Pyrrolidinobutyrophenone, 4-Fluoro-α-PBP[29]
    4-Methoxy-α-Pyrrolidinobutyrophenone, 4-MeO-α-PBP[30]
    4'-Methyl-α-pyrrolidinobutiophenone, MPBP, 4-Me-α-PBP
    5-PPDI, Indanyl-α-PBP
    TH-PBP, Cyclohexane-α-PBP
    α-Pyrrolidinobutiothiophenone, α-PBT[31]
    α-Pyrrolidinopentiophenone, α-PVP, βk-Prolintane, O-2387
    3',4'-Dimethoxy-α-Pyrrolidinopentiophenone, 3,4-DMPV
    4'-Bromo-α-Pyrrolidinopentiophenone, 4-Bromo-α-PVP
    4'-Chloro-α-Pyrrolidinopentiophenone, 4-Chloro-α-PVP
    4'-Fluoro-α-Pyrrolidinopentiophenone, 4-Fluoro-PVP, 4-Fluoro-α-PVP[25]
    4'-Methoxy-α-Pyrrolidinopentiophenone, 4-MeO-α-PVP, 4-MeO-PVP, MOPVP
    Pyrovalerone, 4-Me-α-PVP, Centroton, Thymergix, O-2371
    5-Dihydrobenzofuranpyrovalerone, 5-DBFPV [32]
    Methylenedioxypyrovalerone, MDPV
    Naphyrone, Naphthylpyrovalerone, O-2482
    Pyrophenidone, α-Phenyl-Pyrovalerone
    Indapyrophenidone, Indanyl-α-Phenyl-Pyrovalerone
    α-Pyrrolidinopentiothiophenone, α-PVT
    α-Pyrrolidinohexiophenone, α-PHP, PV-7
    3',4'-Dimethoxy-α-PHP, 3,4-DMPH[14]
    4'-Fluoro-α-pyrrolidinohexiophenone, 4-Fluoro-α-PHP
    4'-Methyl-α-pyrrolidinohexiophenone, MPHP, 4-Me-α-PHP, PV-4
    4'-Methoxy-α-pyrrolidinohexiophenone, 4-MeO-α-PHP
    TH-PHP, Cyclohexane-α-PHP
    5-BPDI, Indanyl-α-PHP
    Methylenedioxypyrrolidinohexiophenone, MDPHP [33]
    TH-PVP, Cyclohexane-α-PVP
    α-Pyrrolidinoheptiphenone, PV-8, α-PHPP[34]
    4'-Fluoro-α-Pyrrolidinoheptiophenone, 4-Fluoro-PV-8, 4-Fluoro-α-PHPP[25]
    4'-Methoxy-α-Pyrrolidinoheptiophenone, 4-MeO-PV-8, 4-MeO-α-PHPP
    α-Pyrrolidinooctanophenone, PV-9, α-POP[25]
    4'-Fluoro-α-Pyrrolidinooctanophenone, 4-Fluoro-PV-9, 4-Fluoro-α-POP[35]
    4'-Methoxy-α-Pyrrolidinooctanophenone, 4-MeO-PV-9, 4-MeO-α-POP[36]
    α-Pyrrolidinononanophenone, PV-10, α-PNP [37]

Thiophenes

Thiophenes are stimulant drugs which are analogues of amphetamine or cathinone where the phenyl ring has been replaced by thiophene.

    Thiopropamine
    Methiopropamine, MPA
    Thiothinone, βk-MPA

Tropanes and Piperidines

Tropane alkaloids occur in plants of the families erythroxylaceae (including coca). Piperidine and its derivatives are ubiquitous building blocks in the synthesis of many pharmaceuticals and fine chemicals.

    2-Diphenylmethylpyrrolidine, Desoxy-D2PM, 2-Benzhydrylpyrrolidine
    3,4-Dichloromethylphenidate, 3,4-CTMP
    4'-Fluorococaine, 4'-FC
    4-Benzylpiperidine, 4-PMPD
    4-Fluoromethylphenidate, 4-FMPH
    4-Methylmethylphenidate, 4-Me-TMP, 4-MMPH
    Benocyclidine
    Desoxypipradrol, 2-DPMP, 2-Diphenylmethylpiperidine
    Dichloropane, RTI-111, O-401
    Ethylphenidate, EPH
    HDEP-28, Ethylnaphthidate
    HDMP-28, Methylnaphthidate
    Isopropylphenidate, IPH, IPPD
    Nitracaine, 4-Nitro-Dimethocaine
    Pipradrol, Meratran
    Propylphenidate, PPH
    Troparil, WIN 35,065-2, β-CPT

Oxazolidines

Oxazolidines are a five-membered ring compounds consisting of three carbons, a nitrogen, and an oxygen. The oxygen and NH are the 1 and 3 positions, respectively. In oxazolidine derivatives, there is always a carbon between the oxygen and the nitrogen.

    4-Methylaminorex, 4-MAR
    4,4'-Dimethylaminorex, 4,4'-DMAR, "Serotoni"

Cyclopropanes

Cyclopropane is a cycloalkane molecule with the molecular formula C3H6, consisting of three carbon atoms linked to each other to form a ring, with each carbon atom bearing two hydrogen atoms resulting in D3h molecular symmetry. Cyclopropane rings are found in numerous biomolecules and pharmaceutical drugs.

    2-PTC, 2-(4-methylphenyl)-cyclopropanamine
    3,4-DFPTC, 2-(3,4-difluorophenyl)-cyclopropanamine

Phenylmorpholines

Phenylmorpholines are a class of stimulants containing a phenethylamine skeleton in which the terminal amine is incorporated into a morpholine ring.

    Isophenmetrazine, 5-methyl-2-phenylmorpholine, PAL-730
    2-Hydroxy-4'-Ethylphenmetrazine, 2-HO-4'-EPM, 2-Hydroxyphenmetetrazine, N-Ethylphenmetrazol
    3,4-Methylenedioxyphendimetrazine, MDMPM
    3-Fluorophenetrazine, 3-FPE
    3-Fluorophenmetrazine, 3-FPM, PAL-593
    3-Methylphenmetrazine, 3-MPM, PAL-773
    N-Ethylphenmetrazine, 4'-EPM, Phenmetetrazine
    4-Methylphenmetrazine, 4-MPM
    6-Methylphenmetrazine, 6-MPM
    G-130
    Methylmorphenate
    PDM-35, 5-Methylphenmetrazine, 5-MPM
    Phenetrazine, PE
    Viloxazine

Phenylacetamides

    2-PA, 2-Phenylacetamide
    2-PTA, 2-(4-methylphenyl)acetamide

Misc

    1,3-Dimethylbutylamine, 1,3-DMBA, "AMP-Citrate"
    2-AI
    2-MPPP, 2-methyl-1-phenyl-3-(piperidin-1-yl)propan-1-one
    3-(diethylamino)-2,2-dimethylpropyl 4-fluorobenzoate
    Amfonelic acid, AFA, WIN 25,978
    Camfetamine
    CRL-40,940, Bisfluoromodafinil
    CRL-40,941, Fladrafinil, Fluorafinil
    Diclofensine, Ro 8-4650
    Dimethocaine, Larocaine
    Homomazindol
    Mephtetramine, MTTA[38]
    Methylhexanamine, DMAA
    Modafiendz, Methyldifluoromodafinil

 




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